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Development of migraine nasal spray

Migraine is the 3rd most prevalent illness and one of the most common neurological diseases in the world. It is estimated that around 1.04 billion people worldwide have been diagnosed with migraines. One of the symptoms of migraine is a one-sided pulsating headache with average to severe intensity which is aggravated by physical activity. It is often accompanied by an aversion to light and sound and with nausea or vomiting, lasting from 4 to 72 hours. About 20 million migraine attack occurs every day. Three times more adult women suffer from migraine than adult men. About 10% of the children between ages 5-15 suffer from the disease. About 50% of women with migraine have more than one attack during a month. In addition to disability, migraine increases the risk of other mental and physical problems. It imposes huge financial and psychological costs on families, companies, and countries. The average health costs of a family with a migraine patient are 70% more than those of a family without such a member.
 
As someone who has suffered from migraines for years, MIM Pharma knew firsthand the debilitating effects we can have on a person’s life. We were determined to develop a solution that could provide fast and effective relief for those who experience migraines.
 
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Our team of top researchers and medical experts explored the underlying causes of migraines and developed a formula based on natural ingredients that would target them directly. After years of research and development, we finally succeeded in creating a breakthrough solution that could provide rapid relief from even the most severe migraine symptoms.
 
 
But our researchers didn’t stop there. We knew that simply creating a solution wasn’t enough we wanted to make it accessible to those who needed it most. So we work tirelessly to bring our migraine solution to market, ensuring that it is widely available and affordable for those who needed it.
 
 
We want to help countless people to reclaim their lives from the grip of migraines, allowing them to enjoy the things they love without fear of debilitating pain and discomfort. And MIM Pharma continues to innovate, always striving to find new and better ways to help those who suffer from migraines to live happier, healthier lives.
 
 
MIM Pharma’s migraine nasal spray has passed all the requirements and clinical trials that were performed based on the International Headache Society (IHS) guidelines on 500 patients with remarkable results.

Mechanism Of Action

Results from clinical trial, migraine patients with episodic and chronic headaches have shown a significant decrease in their severity and clinical symptoms indices after using MIM Pharma’s migraine nasal spray. The patients suffering from “medication overuse headache” (MOH) also benefitted from migraine nasal spray, but usually throughout a longer period of time with similar or even better results of treatment. Patients with migraine accompanied by cluster and tension headaches also had their migraines decreased by using MIM Pharma’s migraine nasal spray. But the reduction of other types of headaches requires special treatments and counseling by neurologists. MIM Pharma’s migraine nasal spray has proven effective in various kinds of migraines in different people for different reasons. In fact, the change in the diameter of the blood vessels in the head (the brain) for managing headaches, enhancing melatonin secretion to improve sleep quality, and biological rhythms and decreasing the free nitric acid in the blood are among the powerful action mechanisms of the nasal spray.

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Introduction

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Discovery

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Pre-Clinical Testing

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Clinical Trials